MORF4L1 抗体 (AA 31-80)
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北京 101111
Quick Overview for MORF4L1 抗体 (AA 31-80) (ABIN1534168)
抗原
See all MORF4L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-80
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原理
- MRG15 Antibody
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特异性
- MRG15 Polyclonal Antibody detects endogenous levels of MRG15 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MORF4L1. AA range:31-80
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亚型
- IgG
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anti-Mortality Factor 4 Like 1 (MORF4L1) (N-Term) antibody
Verified MORF4L1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) antibodyMORF4L1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (AA 251-295) antibodyMORF4L1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠, Pig, 猴, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (Middle Region) antibodyMORF4L1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (AA 1-100) antibodyMORF4L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B6 unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (Middle Region) antibodyMORF4L1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (AA 1-100) antibodyMORF4L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (AA 1-100) antibodyMORF4L1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (N-Term) antibodyMORF4L1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mortality Factor 4 Like 1 (MORF4L1) (AA 328-360) antibodyMORF4L1 适用: 人 WB 宿主: 兔 Polyclonal RB54237 unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
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别名
- MORF4L1
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背景
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Synonyms: MORF4L1, MRG15, FWP006, HSPC008, HSPC061, PP368, Mortality factor 4-like protein 1, MORF-related gene 15 protein, Protein MSL3-1, Transcription factor-like protein MRG15
Background: function:Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.,similarity:Belongs to the MRG family.,subunit:Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit HTATIP/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and EAF6. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the HTATIP/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the mSin3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. MORF4L1 interacts with RB1 and MYST1. MORF4L1 may also interact with PHF12 and one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors. Interacts with the N-terminus of MRFAP1. Found in a complex composed of MORF4L1, MRFAP1 and RB1.,
Gene Name: MORF4L1
Protein Name: Mortality factor 4-like protein 1
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分子量
- 41 kDa
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基因ID
- 10933
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OMIM
- 607303
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UniProt
- Q9UBU8
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途径
- Chromatin Binding
抗原
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