DBF4 抗体 (AA 10-59)
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北京 101111
Quick Overview for DBF4 抗体 (AA 10-59) (ABIN1534167)
抗原
See all DBF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- Dbf4 Antibody
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特异性
- Dbf4 Polyclonal Antibody detects endogenous levels of Dbf4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human DBF4. AA range:10-59
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亚型
- IgG
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anti-DBF4 Homolog (DBF4) (AA 2-98) antibody
DBF4 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6G9 unconjugated
anti-DBF4 Homolog (DBF4) (Internal Region) antibodyDBF4 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DBF4 Homolog (DBF4) (AA 101-281) antibodyDBF4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DBF4 Homolog (DBF4) antibodyDBF4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5370 unconjugated Recombinant Antibody
anti-DBF4 Homolog (DBF4) antibodyDBF4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3815 unconjugated Recombinant Antibody
anti-DBF4 Homolog (DBF4) (AA 2-98) antibodyDBF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DBF4 Homolog (DBF4) (AA 295-665) antibodyDBF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-DBF4 Homolog (DBF4) (N-Term) antibodyDBF4 适用: 人, Cow, Pig WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DBF4 Homolog (DBF4) (Internal Region) antibodyVerified DBF4 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-DBF4 Homolog (DBF4) (N-Term) antibodyDBF4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DBF4 (DBF4 Homolog (DBF4))
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别名
- DBF4
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背景
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Synonyms: DBF4, ASK, DBF4A, ZDBF1, Protein DBF4 homolog A, Activator of S phase kinase, Chiffon homolog A, DBF4-type zinc finger-containing protein 1
Background: function:Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.,induction:Induced in G1 phase at low level, increased during G1-S phase and remain high during S and G2-M phase.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 DBF4-type zinc finger.,similarity:Contains 2 BRCT domains.,subunit:Forms a complex with CDC7. Note that CDC7 forms distinct complex either with DBF4A or DBF4B. Such complexes are stable upon replication stress. Interacts with MEN1, MCM2, ORC2L, ORC4L and ORC6L.,tissue specificity:Highly expressed in testis and thymus. Expressed also in most cancer cells lines.,
Gene Name: DBF4
Protein Name: Protein DBF4 homolog A
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分子量
- 76 kDa
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基因ID
- 10926
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OMIM
- 604281
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UniProt
- Q9UBU7
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途径
- Mitotic G1-G1/S Phases, DNA Replication
抗原
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