ERAP1 抗体 (AA 441-490)
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北京 101111
Quick Overview for ERAP1 抗体 (AA 441-490) (ABIN1534157)
抗原
See all ERAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 441-490
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原理
- ERAP1 Antibody
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特异性
- ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ARTS-1. AA range:441-490
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
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别名
- ARTS-1
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背景
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Synonyms: ERAP1, APPILS, ARTS1, KIAA0525, Endoplasmic reticulum aminopeptidase 1, ARTS-1, Adipocyte-derived leucine aminopeptidase, A-LAP, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP, Type 1 tumor necrosis facto
Background: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010],
Gene Name: ERAP1
Protein Name: Endoplasmic reticulum aminopeptidase 1
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分子量
- 107 kDa
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基因ID
- 51752
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OMIM
- 606832
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UniProt
- Q9NZ08
抗原
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