ZAK 抗体 (AA 701-750)
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Quick Overview for ZAK 抗体 (AA 701-750) (ABIN1534154)
抗原
See all ZAK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 701-750
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原理
- MLTK Antibody
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特异性
- MLTK Polyclonal Antibody detects endogenous levels of MLTK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MLTK. AA range:701-750
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
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别名
- MLTK
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背景
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Synonyms: MLTK, ZAK, HCCS4, Mitogen-activated protein kinase kinase kinase MLT, Human cervical cancer suppressor gene 4 protein, HCCS-4, Leucine zipper- and sterile alpha motif-containing kinase, MLK-like mitogen-activated protein triple kinase, Mixe
Background: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Gene Name: MLTK
Protein Name: Mitogen-activated protein kinase kinase kinase MLT
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分子量
- 91 kDa
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基因ID
- 51776
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OMIM
- 609479
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UniProt
- Q9NYL2
抗原
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