CREBZF 抗体 (AA 221-270)
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北京 101111
Quick Overview for CREBZF 抗体 (AA 221-270) (ABIN1534147)
抗原
See all CREBZF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-270
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原理
- Zhangfei Antibody
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特异性
- Zhangfei Polyclonal Antibody detects endogenous levels of Zhangfei protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CREBZF. AA range:221-270
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))
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别名
- CREBZF
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背景
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Synonyms: CREBZF, ZF, CREB/ATF bZIP transcription factor, Host cell factor-binding transcription factor Zhangfei, HCF-binding transcription factor Zhangfei
Background: function:Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.,miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1.,subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity.,tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.,
Gene Name: CREBZF
Protein Name: CREB/ATF bZIP transcription factor
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分子量
- 28 kDa
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基因ID
- 58487
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OMIM
- 606444
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UniProt
- Q9NS37
抗原
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