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CREBZF 抗体 (AA 221-270)

The 兔 多克隆 anti-CREBZF antibody is suitable to detect CREBZF in samples from 人 和 小鼠. It has been validated for WB, ELISA, IF 和 IHC.
产品编号 ABIN1534147
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CREBZF 抗体 (AA 221-270) (ABIN1534147)

抗原

See all CREBZF 抗体
CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

适用

  • 34
  • 21
  • 8
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 34
兔

克隆类型

  • 34
多克隆

标记

  • 22
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CREBZF antibody is un-conjugated

应用范围

  • 27
  • 15
  • 6
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-270

    原理

    Zhangfei Antibody

    特异性

    Zhangfei Polyclonal Antibody detects endogenous levels of Zhangfei protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CREBZF. AA range:221-270

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

    别名

    CREBZF

    背景

    Synonyms: CREBZF, ZF, CREB/ATF bZIP transcription factor, Host cell factor-binding transcription factor Zhangfei, HCF-binding transcription factor Zhangfei

    Background: function:Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.,miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1.,subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity.,tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.,

    Gene Name: CREBZF

    Protein Name: CREB/ATF bZIP transcription factor

    分子量

    28 kDa

    基因ID

    58487

    OMIM

    606444

    UniProt

    Q9NS37
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