TINF2 抗体 (AA 71-120)
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Quick Overview for TINF2 抗体 (AA 71-120) (ABIN1534093)
抗原
See all TINF2 (TIN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-120
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原理
- TIN2 Antibody
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特异性
- TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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别名
- TINF2
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背景
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Synonyms: TINF2, TIN2, TERF1-interacting nuclear factor 2, TRF1-interacting nuclear protein 2
Background: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage.The protein encoded by this gene is a critical part of shelterin, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],
Gene Name: TINF2
Protein Name: TERF1-interacting nuclear factor 2
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分子量
- 50 kDa
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基因ID
- 26277
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OMIM
- 127550
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UniProt
- Q9BSI4
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途径
- Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
抗原
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