MED12 抗体 (AA 611-660)
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北京 101111
Quick Overview for MED12 抗体 (AA 611-660) (ABIN1534053)
抗原
See all MED12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 611-660
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原理
- TRAP230 Antibody
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特异性
- TRAP230 Polyclonal Antibody detects endogenous levels of TRAP230 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MED12. AA range:611-660
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亚型
- IgG
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anti-Mediator Complex Subunit 12 (MED12) (AA 2127-2177) antibody
MED12 适用: 人, 小鼠 IHC, WB, IP, ICC, FACS 宿主: 兔 Monoclonal BLR084G unconjugated Recombinant Antibody
anti-Mediator Complex Subunit 12 (MED12) (AA 1991-2025), (C-Term) antibodyMED12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52354 unconjugated
anti-Mediator Complex Subunit 12 (MED12) (C-Term) antibodyMED12 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (Internal Region) antibodyMED12 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 1742-2011) antibodyMED12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) antibodyMED12 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (C-Term) antibodyMED12 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 1829-1941) antibodyMED12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 251-350) antibodyMED12 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MED12 (Mediator Complex Subunit 12 (MED12))
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别名
- MED12
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背景
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Synonyms: MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230, Mediator of RNA polymerase II transcription subunit 12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45, Mediator complex subunit 12, OPA-containing prote
Background: The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which containsThe protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009],
Gene Name: MED12
Protein Name: Mediator of RNA polymerase II transcription subunit 12
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分子量
- 247 kDa
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基因ID
- 9968
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OMIM
- 300188
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UniProt
- Q93074
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
抗原
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