ATPBD3 抗体 (AA 291-340)
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Quick Overview for ATPBD3 抗体 (AA 291-340) (ABIN1533976)
抗原
See all ATPBD3 (CTU1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 291-340
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原理
- ATPBD3 Antibody
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特异性
- ATPBD3 Polyclonal Antibody detects endogenous levels of ATPBD3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ATPBD3. AA range:291-340
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))
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别名
- ATPBD3
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背景
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Synonyms: CTU1, ATPBD3, NCS6, Cytoplasmic tRNA 2-thiolation protein 1, ATP-binding domain-containing protein 3, Cancer-associated gene protein, Cytoplasmic tRNA adenylyltransferase 1
Background: function:Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification, 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,
Gene Name: CTU1
Protein Name: Cytoplasmic tRNA 2-thiolation protein 1
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分子量
- 36 kDa
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基因ID
- 90353
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OMIM
- 612694
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UniProt
- Q7Z7A3
抗原
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