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STRADA 抗体 (AA 11-60)

The 兔 多克隆 anti-STRADA antibody (ABIN1533974) specifically detects STRADA in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1533974
发货至: 中国
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Quick Overview for STRADA 抗体 (AA 11-60) (ABIN1533974)

抗原

See all STRADA 抗体
STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

适用

  • 65
  • 15
  • 7
  • 5
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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 62
  • 3
兔

克隆类型

  • 63
  • 2
多克隆

标记

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  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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This STRADA antibody is un-conjugated

应用范围

  • 58
  • 27
  • 13
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  • 12
  • 8
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 9
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-60

    原理

    Strad Antibody

    特异性

    Strad Polyclonal Antibody detects endogenous levels of Strad protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human STRAD. AA range:11-60

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

    别名

    STRAD

    背景

    Synonyms: STRADA; LYK5; STRAD; STE20-related kinase adapter protein alpha; STRAD alpha; STE20-related adapter protein; Serologically defined breast cancer antigen NY-BR-96

    Background: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a ' pseudokinase' . The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009],

    Gene Name: STRADA

    Protein Name: STE20-related kinase adapter protein alpha

    分子量

    48 kDa

    基因ID

    92335

    OMIM

    608626

    UniProt

    Q7RTN6

    途径

    AMPK Signaling
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