MLK4 抗体 (AA 631-680)
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Quick Overview for MLK4 抗体 (AA 631-680) (ABIN1533952)
抗原
See all MLK4 (KIAA1804) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 631-680
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原理
- MLK4 Antibody
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特异性
- MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))
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别名
- MAP3KL4
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背景
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Synonyms: MLK4, KIAA1804, Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,
Gene Name: MLK4
Protein Name: Mitogen-activated protein kinase kinase kinase MLK4
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分子量
- 113 kDa
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基因ID
- 84451
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UniProt
- Q5TCX8
抗原
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