SMAD1 抗体 (AA 10-59)
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Quick Overview for SMAD1 抗体 (AA 10-59) (ABIN1533926)
抗原
See all SMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- Smad1/5/9 Antibody
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特异性
- Smad1/5/9 Polyclonal Antibody detects endogenous levels of Smad1/5/9 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Smad1/5/9. AA range:10-59
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亚型
- IgG
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anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-240) antibody
SMAD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibodySMAD1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2A1 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-110) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 202-335) antibodySMAD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-330) antibodySMAD1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1356CT119-18-55 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB43846 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-110) antibodySMAD1 适用: 人, 小鼠, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 4E12H10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-466) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A1 unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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别名
- Smad1/5/9
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背景
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Synonyms: SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein
Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
Gene Name: SMAD1/SMAD5/SMAD9
Protein Name: Mothers against decapentaplegic homolog 1/Mothers against decapentaplegic homolog 5/Mothers against decapentaplegic homolog 9
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分子量
- 52 kDa
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基因ID
- 4086, 4090, 4093
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OMIM
- 601595
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UniProt
- Q15797
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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