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MED1 抗体 (AA 641-690)

The 兔 多克隆 anti-MED1 antibody (ABIN1533917) specifically detects MED1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1533917
发货至: 中国
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Quick Overview for MED1 抗体 (AA 641-690) (ABIN1533917)

抗原

See all MED1 抗体
MED1 (Mediator Complex Subunit 1 (MED1))

适用

  • 57
  • 27
  • 14
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 50
  • 5
  • 2
兔

克隆类型

  • 50
  • 7
多克隆

标记

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  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MED1 antibody is un-conjugated

应用范围

  • 27
  • 19
  • 17
  • 14
  • 13
  • 13
  • 8
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 641-690

    原理

    TRAP220 Antibody

    特异性

    TRAP220 Polyclonal Antibody detects endogenous levels of TRAP220 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MED1. AA range:641-690

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MED1 (Mediator Complex Subunit 1 (MED1))

    别名

    MED1

    背景

    Synonyms: MED1, ARC205, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2, Mediator of RNA polymerase II transcription subunit 1, Activator-recruited cofactor 205 kDa component, ARC205, Mediator complex subunit 1, Peroxiso

    Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008],

    Gene Name: MED1

    Protein Name: Mediator of RNA polymerase II transcription subunit 1

    分子量

    168 kDa

    基因ID

    5469

    OMIM

    604311

    UniProt

    Q15648

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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