SURF1 抗体 (AA 171-220)
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北京 101111
Quick Overview for SURF1 抗体 (AA 171-220) (ABIN1533909)
抗原
See all SURF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-220
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原理
- SURF-1 Antibody
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特异性
- SURF-1 Polyclonal Antibody detects endogenous levels of SURF-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human SURF1. AA range:171-220
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SURF1 (Surfeit 1 (SURF1))
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别名
- SURF1
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背景
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Synonyms: SURF1, SURF-1, Surfeit locus protein 1
Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008],
Gene Name: SURF1
Protein Name: Surfeit locus protein 1
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分子量
- 33 kDa
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基因ID
- 6834
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OMIM
- 185620
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UniProt
- Q15526
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途径
- Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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