TRIM25 抗体 (AA 201-250)
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Quick Overview for TRIM25 抗体 (AA 201-250) (ABIN1533885)
抗原
See all TRIM25 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-250
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原理
- EFP Antibody
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特异性
- EFP Polyclonal Antibody detects endogenous levels of EFP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ZNF147. AA range:201-250
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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别名
- ZNF147
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背景
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Synonyms: TRIM25, EFP, RNF147, ZNF147, E3 ubiquitin/ISG15 ligase TRIM25, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Zinc finger protein 147
Background: The protein encoded byThis gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008],
Gene Name: TRIM25
Protein Name: E3 ubiquitin/ISG15 ligase TRIM25
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分子量
- 70 kDa
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基因ID
- 7706
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OMIM
- 600453
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UniProt
- Q14258
抗原
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