DMPK 抗体 (AA 11-60)
Our Local Distributor
北京 101111
Quick Overview for DMPK 抗体 (AA 11-60) (ABIN1533843)
抗原
See all DMPK 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 11-60
-
原理
- DMPK Antibody
-
特异性
- DMPK Polyclonal Antibody detects endogenous levels of DMPK protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human DMPK. AA range:11-60
-
亚型
- IgG
-
-
anti-Dystrophia Myotonica-Protein Kinase (DMPK) antibody
DMPK 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 303-420) antibodyDMPK 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 243-424) antibodyDMPK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 323-372) antibodyDMPK 适用: 人, 小鼠, Cow, 犬, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Center) antibodyDMPK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 11-39), (N-Term) antibodyDMPK 适用: 人 WB 宿主: 兔 Polyclonal RB36813 unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
-
别名
- DMPK
-
背景
-
Synonyms: DMPK; DM1PK; MDPK; Myotonin-protein kinase; MT-PK; DM-kinase; DMK; DM1 protein kinase; DMPK; Myotonic dystrophy protein kinase
Background: The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2016],
Gene Name: DMPK
Protein Name: Myotonin-protein kinase
-
分子量
- 70 kDa
-
基因ID
- 1760
-
OMIM
- 605377
-
UniProt
- Q09013
-
途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
-
