MVK 抗体 (AA 151-200)
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北京 101111
Quick Overview for MVK 抗体 (AA 151-200) (ABIN1533828)
抗原
See all MVK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200
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原理
- MVK Antibody
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特异性
- MVK Polyclonal Antibody detects endogenous levels of MVK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Mevalonate Kinase. AA range:151-200
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MVK (Mevalonate Kinase (MVK))
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别名
- Mevalonate Kinase
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背景
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Synonyms: MVK, Mevalonate kinase, MK
Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Gene Name: MVK
Protein Name: Mevalonate kinase
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分子量
- 42 kDa
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基因ID
- 4598
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OMIM
- 251170
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UniProt
- Q03426
抗原
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