Sp3/4 抗体 (AA 671-720)
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Quick Overview for Sp3/4 抗体 (AA 671-720) (ABIN1533821)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 671-720
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原理
- Sp3/4 Antibody
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特异性
- Sp3/4 Polyclonal Antibody detects endogenous levels of Sp3/4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human SP3/4. AA range:671-720
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Sp3/4
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背景
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Synonyms: SP3, Transcription factor Sp3, SPR-2, SP4, Transcription factor Sp4, SPR-1
Background: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010],
Gene Name: SP3/SP4
Protein Name: Transcription factor Sp3/4
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分子量
- 82 kDa
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基因ID
- 6670, 6671
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OMIM
- 601804
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UniProt
- Q02447
抗原
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