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TMPRSS3 抗体 (AA 405-454)

The 兔 多克隆 anti-TMPRSS3 antibody is suitable to detect TMPRSS3 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1533796
发货至: 中国
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Quick Overview for TMPRSS3 抗体 (AA 405-454) (ABIN1533796)

抗原

See all TMPRSS3 抗体
TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

适用

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人, 小鼠

宿主

  • 45
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兔

克隆类型

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  • 2
多克隆

标记

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This TMPRSS3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 405-454

    原理

    TMPRSS3 Antibody

    特异性

    TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human TMPRSS3. AA range:405-454

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

    别名

    TMPRSS3

    背景

    Synonyms: TMPRSS3, ECHOS1, TADG12, Transmembrane protease serine 3, Serine protease TADG-12, Tumor-associated differentially-expressed gene 12 protein

    Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders.This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012],

    Gene Name: TMPRSS3

    Protein Name: Transmembrane protease serine 3

    分子量

    49 kDa

    基因ID

    64699

    OMIM

    601072

    UniProt

    P57727

    途径

    Sensory Perception of Sound
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