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ETV1 抗体 (AA 10-59)

The 兔 多克隆 anti-ETV1 antibody (ABIN484374) specifically detects ETV1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN484374
发货至: 中国
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Quick Overview for ETV1 抗体 (AA 10-59) (ABIN484374)

抗原

See all ETV1 抗体
ETV1 (Ets Variant 1 (ETV1))

适用

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  • 4
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  • 1
人, 小鼠

宿主

  • 44
  • 5
  • 1
兔

克隆类型

  • 46
  • 4
多克隆

标记

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This ETV1 antibody is un-conjugated

应用范围

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  • 14
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  • 7
  • 5
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  • 1
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 10-59

    原理

    ER81 Antibody

    特异性

    ER81 Polyclonal Antibody detects endogenous levels of ER81 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ER81. AA range:10-59

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ETV1 (Ets Variant 1 (ETV1))

    别名

    ER81

    背景

    Synonyms: ETV1; ER81; ETS translocation variant 1; Ets-related protein 81

    Background: This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'.The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alte

    Gene Name: ETV1

    Protein Name: ETS translocation variant 1

    分子量

    55 kDa

    基因ID

    2115

    OMIM

    600541

    UniProt

    P50549
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