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ATRX 抗体 (AA 111-160)

The 兔 多克隆 anti-ATRX antibody is suitable to detect ATRX in samples from 人 和 小鼠. It has been validated for ELISA 和 IF.
产品编号 ABIN1533739
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for ATRX 抗体 (AA 111-160) (ABIN1533739)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

适用

  • 100
  • 28
  • 14
  • 3
  • 2
  • 2
人, 小鼠

宿主

  • 61
  • 38
  • 1
兔

克隆类型

  • 54
  • 46
多克隆

标记

  • 55
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATRX antibody is un-conjugated

应用范围

  • 47
  • 42
  • 32
  • 22
  • 13
  • 13
  • 9
  • 9
  • 5
  • 3
  • 1
  • 1
ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 9
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-160

    原理

    ATRX Antibody

    特异性

    ATRX Polyclonal Antibody detects endogenous levels of ATRX protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ATRX. AA range:111-160

    亚型

    IgG
  • 应用备注

    IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    背景

    Synonyms: ATRX, RAD54L, XH2, Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX

    Background: ATRX, chromatin remodeler(ATRX) Homo sapiens The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2013],

    Gene Name: ATRX

    Protein Name: Transcriptional regulator ATRX

    分子量

    282 kDa

    基因ID

    546

    OMIM

    300032

    UniProt

    P46100
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