CBX5 抗体 (AA 41-90)
Our Local Distributor
北京 101111
Quick Overview for CBX5 抗体 (AA 41-90) (ABIN1533736)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 41-90
-
原理
- HP1α Antibody
-
特异性
- HP1α Polyclonal Antibody detects endogenous levels of HP1α protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human CBX5. AA range:41-90
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CBX5 (Chromobox Homolog 5 (CBX5))
-
别名
- CBX5
-
背景
-
Synonyms: CBX5, HP1A, Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha
Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
Gene Name: CBX5
Protein Name: Chromobox protein homolog 5
-
分子量
- 22 kDa
-
基因ID
- 23468
-
OMIM
- 604478
-
UniProt
- P45973
抗原
-