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ADRA2C 抗体 (AA 336-385)

The 兔 多克隆 anti-ADRA2C antibody is suitable to detect ADRA2C in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1533643
发货至: 中国
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Quick Overview for ADRA2C 抗体 (AA 336-385) (ABIN1533643)

抗原

See all ADRA2C 抗体
ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

  • 59
  • 36
多克隆

标记

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This ADRA2C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 336-385

    原理

    AR α2C Antibody

    特异性

    AR α2C Polyclonal Antibody detects endogenous levels of AR α2C protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2C. AA range:336-385

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

    别名

    Adrenergic Receptor alpha-2C

    背景

    Synonyms: ADRA2C, ADRA2L2, ADRA2RL2, Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR

    Background: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity.This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],

    Gene Name: ADRA2C

    Protein Name: Alpha-2C adrenergic receptor

    分子量

    49 kDa

    基因ID

    152

    OMIM

    104250

    UniProt

    P18825

    途径

    EGFR Signaling Pathway, cAMP Metabolic Process
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