ADRA2C 抗体 (AA 336-385)
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北京 101111
Quick Overview for ADRA2C 抗体 (AA 336-385) (ABIN1533643)
抗原
See all ADRA2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 336-385
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原理
- AR α2C Antibody
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特异性
- AR α2C Polyclonal Antibody detects endogenous levels of AR α2C protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2C. AA range:336-385
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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别名
- Adrenergic Receptor alpha-2C
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背景
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Synonyms: ADRA2C, ADRA2L2, ADRA2RL2, Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR
Background: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity.This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],
Gene Name: ADRA2C
Protein Name: Alpha-2C adrenergic receptor
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分子量
- 49 kDa
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基因ID
- 152
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OMIM
- 104250
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UniProt
- P18825
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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