MYF5 抗体 (AA 61-110)
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北京 101111
Quick Overview for MYF5 抗体 (AA 61-110) (ABIN1533615)
抗原
See all MYF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-110
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原理
- Myf-5 Antibody
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特异性
- Myf-5 Polyclonal Antibody detects endogenous levels of Myf-5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MYF5. AA range:61-110
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亚型
- IgG
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应用备注
- Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MYF5 (Myogenic Factor 5 (MYF5))
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别名
- MYF5
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背景
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Synonyms: MYF5, BHLHC2, Myogenic factor 5, Myf-5, Class C basic helix-loop-helix protein 2, bHLHc2
Background: von Hippel-Lindau tumor suppressor(VHL) Homo sapiens Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome.The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Gene Name: MYF5
Protein Name: Myogenic factor 5
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分子量
- 28 kDa
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OMIM
- 159990
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UniProt
- P13349
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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