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HARS1/Jo-1 抗体 (AA 460-509)

The 兔 多克隆 anti-HARS1/Jo-1 antibody (ABIN1533611) specifically detects HARS1/Jo-1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1533611
发货至: 中国
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Quick Overview for HARS1/Jo-1 抗体 (AA 460-509) (ABIN1533611)

抗原

See all HARS1/Jo-1 (HARS1) 抗体
HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))

适用

  • 70
  • 18
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  • 1
  • 1
人, 小鼠

宿主

  • 52
  • 12
  • 6
兔

克隆类型

  • 50
  • 19
多克隆

标记

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  • 1
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This HARS1/Jo-1 antibody is un-conjugated

应用范围

  • 53
  • 22
  • 13
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  • 10
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  • 7
  • 6
  • 4
  • 3
  • 3
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 460-509

    原理

    HisRS Antibody

    特异性

    HisRS Polyclonal Antibody detects endogenous levels of HisRS protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human HARS. AA range:460-509

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))

    别名

    HARS

    背景

    Synonyms: HARS, HRS, Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS

    Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids.The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

    Gene Name: HARS

    Protein Name: Histidine--tRNA ligase cytoplasmic

    分子量

    57 kDa

    基因ID

    3035

    OMIM

    142810

    UniProt

    P12081
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