PSKH1 抗体 (AA 261-310)
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Quick Overview for PSKH1 抗体 (AA 261-310) (ABIN1533610)
抗原
See all PSKH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310
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原理
- PSK-H1 Antibody
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特异性
- PSK-H1 Polyclonal Antibody detects endogenous levels of PSK-H1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human KPSH1. AA range:261-310
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亚型
- IgG
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anti-Protein Serine Kinase H1 (PSKH1) antibody
PSKH1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Serine Kinase H1 (PSKH1) antibodyPSKH1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Serine Kinase H1 (PSKH1) (Internal Region) antibodyPSKH1 适用: 人, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Serine Kinase H1 (PSKH1) (AA 55-91), (N-Term) antibodyPSKH1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8154 unconjugated
anti-Protein Serine Kinase H1 (PSKH1) (Internal Region) antibodyPSKH1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Serine Kinase H1 (PSKH1) (Internal Region) antibodyPSKH1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PSKH1 (Protein Serine Kinase H1 (PSKH1))
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背景
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Synonyms: PSKH1, Serine/threonine-protein kinase H1, Protein serine kinase H1, PSK-H1
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activity depends on Ca(2+) concentration.,function:May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing.,PTM:Autophosphorylated on serine residues.,PTM:Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur.,PTM:Palmitoylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Localized in the Brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes.,subunit:Homodimer.,tissue specificity:Expressed in all tissues and cell lines tested with the highest level of abundance in testis.,
Gene Name: PSKH1
Protein Name: Serine/threonine-protein kinase H1
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分子量
- 48 kDa
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基因ID
- 5681
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OMIM
- 177015
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UniProt
- P11801
抗原
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