MYBL1 抗体 (AA 231-280)
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Quick Overview for MYBL1 抗体 (AA 231-280) (ABIN1533606)
抗原
See all MYBL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-280
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原理
- A-Myb Antibody
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特异性
- A-Myb Polyclonal Antibody detects endogenous levels of A-Myb protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MYBL1 (Myb-Like Protein 1 (MYBL1))
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背景
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Synonyms: MYBL1, AMYB, Myb-related protein A, A-Myb, Myb-like protein 1
Background: function:Strong transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,
Gene Name: MYBL1
Protein Name: Myb-related protein A
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分子量
- 85 kDa
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基因ID
- 4603
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OMIM
- 159405
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UniProt
- P10243
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途径
- Cell Division Cycle, Chromatin Binding
抗原
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