PTTG1 抗体 (AA 111-160)
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北京 101111
Quick Overview for PTTG1 抗体 (AA 111-160) (ABIN1533575)
抗原
See all PTTG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-160
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原理
- PTTG1/2/3 Antibody
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特异性
- PTTG1/2/3 Polyclonal Antibody detects endogenous levels of PTTG1/2/3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PTTG1. AA range:111-160
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亚型
- IgG
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anti-Pituitary Tumor-Transforming 1 (PTTG1) antibody
KD Validated PTTG1 适用: 人 WB, ICC, FACS, IF (p) 宿主: 兔 Monoclonal 24GB1495 unconjugated Recombinant Antibody
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-199) antibodyPTTG1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (Internal Region) antibodyVerified PTTG1 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 16-45), (N-Term) antibodyPTTG1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18596 unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-202) antibodyPTTG1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) antibodyPTTG1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (C-Term) antibodyPTTG1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 93-113) antibodyPTTG1 适用: 人 IF 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 101-202) antibodyPTTG1 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) antibodyPTTG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
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别名
- PTTG1
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背景
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Synonyms: PTTG1, EAP1, PTTG, TUTR1, Securin, Esp1-associated protein, Pituitary tumor-transforming gene 1 protein, Tumor-transforming protein 1, hPTTG
Background: The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been fo
Gene Name: PTTG1
Protein Name: Securin
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分子量
- 22 kDa
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基因ID
- 9232
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OMIM
- 604147
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UniProt
- O95997
抗原
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