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MBD3 抗体 (AA 221-270)

This 兔 多克隆 antibody specifically detects MBD3 in WB, ELISA 和 IHC. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1533573
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for MBD3 抗体 (AA 221-270) (ABIN1533573)

抗原

See all MBD3 抗体
MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

适用

  • 106
  • 60
  • 48
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 92
  • 12
  • 2
兔

克隆类型

  • 65
  • 41
多克隆

标记

  • 55
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This MBD3 antibody is un-conjugated

应用范围

  • 78
  • 39
  • 34
  • 24
  • 23
  • 17
  • 15
  • 4
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 21
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-270

    原理

    MBD3 Antibody

    特异性

    MBD3 Polyclonal Antibody detects endogenous levels of MBD3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MBD3. AA range:221-270

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

    别名

    MBD3

    背景

    Synonyms: MBD3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3

    Background: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

    Gene Name: MBD3

    Protein Name: Methyl-CpG-binding domain protein 3

    分子量

    32 kDa

    基因ID

    53615

    OMIM

    603573

    UniProt

    O95983

    途径

    Chromatin Binding
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