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MAP4K4 抗体 (AA 406-455)

This 兔 多克隆 antibody specifically detects MAP4K4 in WB, ELISA 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1533570
发货至: 中国
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Quick Overview for MAP4K4 抗体 (AA 406-455) (ABIN1533570)

抗原

See all MAP4K4 抗体
MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

适用

  • 78
  • 32
  • 19
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 72
  • 6
兔

克隆类型

  • 70
  • 8
多克隆

标记

  • 40
  • 5
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MAP4K4 antibody is un-conjugated

应用范围

  • 42
  • 24
  • 21
  • 16
  • 16
  • 11
  • 10
  • 10
  • 8
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 23
    • 12
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 406-455

    原理

    HGK Antibody

    特异性

    HGK Polyclonal Antibody detects endogenous levels of HGK protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MEKKK 4. AA range:406-455

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

    别名

    MEKKK 4

    背景

    Synonyms: MAP4K4, HGK, KIAA0687, NIK, Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase

    Background: mitogen-activated protein kinase kinase kinase kinase 4(MAP4K4) Homo sapiens The protein encoded byThis gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

    Gene Name: MAP4K4

    Protein Name: Mitogen-activated protein kinase kinase kinase kinase 4

    分子量

    142 kDa

    基因ID

    9448

    OMIM

    604666

    UniProt

    O95819
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