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KDM4B 抗体 (AA 351-400)

This 兔 多克隆 antibody specifically detects KDM4B in ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533552
发货至: 中国
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Quick Overview for KDM4B 抗体 (AA 351-400) (ABIN1533552)

抗原

See all KDM4B 抗体
KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

适用

  • 95
  • 28
  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 89
  • 6
兔

克隆类型

  • 76
  • 19
多克隆

标记

  • 41
  • 9
  • 6
  • 6
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
This KDM4B antibody is un-conjugated

应用范围

  • 64
  • 43
  • 27
  • 26
  • 14
  • 14
  • 12
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-400

    原理

    JMJD2B Antibody

    特异性

    JMJD2B Polyclonal Antibody detects endogenous levels of JMJD2B protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human KDM4B. AA range:351-400

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

    别名

    JHD3B

    背景

    Synonyms: KDM4B, JHDM3B, JMJD2B, KIAA0876, Lysine-specific demethylase 4B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B

    Background: cofactor:Binds 1 Fe(2+) ion per subunit.,domain:The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,similarity:Contains 2 PHD-type zinc fingers.,similarity:Contains 2 Tudor domains.,

    Gene Name: KDM4B

    Protein Name: Lysine-specific demethylase 4B

    分子量

    121 kDa

    基因ID

    23030

    OMIM

    609765

    UniProt

    O94953

    途径

    Warburg Effect
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