Hairless 抗体 (AA 41-90)
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Quick Overview for Hairless 抗体 (AA 41-90) (ABIN1533510)
抗原
See all Hairless (HR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-90
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原理
- Hairless Antibody
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特异性
- Hairless Polyclonal Antibody detects endogenous levels of Hairless protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HAIR. AA range:41-90
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亚型
- IgG
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anti-Hairless (HR) (AA 345-460) antibody
HR 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hairless (HR) (AA 697-746) antibodyHR 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hairless (HR) (AA 170-219) antibodyHR 适用: 人, 小鼠, Cow, 犬, Pig, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairless (HR) (C-Term) antibodyHR 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hairless (HR) (N-Term) antibodyHR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hairless (HR) (AA 1090-1189) antibodyHR 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Hairless (HR)
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背景
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Synonyms: HR, Protein hairless
Background: This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014],
Gene Name: HR
Protein Name: Protein hairless
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分子量
- 127 kDa
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基因ID
- 55806
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OMIM
- 602302
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UniProt
- O43593
抗原
-
