T-Box 1 抗体 (AA 311-360)
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北京 101111
Quick Overview for T-Box 1 抗体 (AA 311-360) (ABIN1533506)
抗原
See all T-Box 1 (TBX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360
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原理
- TBX1 Antibody
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特异性
- TBX1 Polyclonal Antibody detects endogenous levels of TBX1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TBX1. AA range:311-360
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- T-Box 1 (TBX1)
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别名
- TBX1
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背景
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Synonyms: TBX1, T-box transcription factor TBX1, T-box protein 1, Testis-specific T-box protein
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: TBX1
Protein Name: T-box transcription factor TBX1
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分子量
- 43 kDa
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基因ID
- 6899
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OMIM
- 188400
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UniProt
- O43435
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途径
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
抗原
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