TRIM24 抗体 (AA 1001-1050)
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北京 101111
Quick Overview for TRIM24 抗体 (AA 1001-1050) (ABIN1533495)
抗原
See all TRIM24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1001-1050
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原理
- TIF1α Antibody
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特异性
- TIF1α Polyclonal Antibody detects endogenous levels of TIF1α protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TRIM24. AA range:1001-1050
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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别名
- TRIM24
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背景
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Synonyms: TRIM24, RNF82, TIF1, TIF1A, Transcription intermediary factor 1-alpha, TIF1-alpha, E3 ubiquitin-protein ligase TRIM24, RING finger protein 82, Tripartite motif-containing protein 24
Background: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: TRIM24
Protein Name: Transcription intermediary factor 1-alpha
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分子量
- 116 kDa
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基因ID
- 8805
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OMIM
- 188550
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UniProt
- O15164
抗原
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