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GAK 抗体 (AA 101-150)

This 兔 多克隆 antibody specifically detects GAK in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1533492
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GAK 抗体 (AA 101-150) (ABIN1533492)

抗原

See all GAK 抗体
GAK (Cyclin G Associated Kinase (GAK))

适用

  • 62
  • 25
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 59
  • 3
兔

克隆类型

  • 61
  • 1
多克隆

标记

  • 28
  • 5
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  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GAK antibody is un-conjugated

应用范围

  • 50
  • 24
  • 22
  • 13
  • 13
  • 10
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-150

    原理

    GAK Antibody

    特异性

    GAK Polyclonal Antibody detects endogenous levels of GAK protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GAK. AA range:101-150

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GAK (Cyclin G Associated Kinase (GAK))

    别名

    GAK

    背景

    Synonyms: GAK; Cyclin-G-associated kinase

    Background: cyclin G associated kinase(GAK) Homo sapiens In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

    Gene Name: GAK

    Protein Name: Cyclin-G-associated kinase

    分子量

    143 kDa

    基因ID

    2580

    OMIM

    602052

    UniProt

    O14976
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