GAK 抗体 (AA 101-150)
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北京 101111
Quick Overview for GAK 抗体 (AA 101-150) (ABIN1533492)
抗原
See all GAK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-150
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原理
- GAK Antibody
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特异性
- GAK Polyclonal Antibody detects endogenous levels of GAK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GAK. AA range:101-150
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GAK (Cyclin G Associated Kinase (GAK))
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别名
- GAK
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背景
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Synonyms: GAK; Cyclin-G-associated kinase
Background: cyclin G associated kinase(GAK) Homo sapiens In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Gene Name: GAK
Protein Name: Cyclin-G-associated kinase
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分子量
- 143 kDa
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基因ID
- 2580
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OMIM
- 602052
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UniProt
- O14976
抗原
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