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RCC1 抗体 (AA 517-566)

The 兔 多克隆 anti-RCC1 antibody (ABIN1533464) specifically detects RCC1 in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1533464
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RCC1 抗体 (AA 517-566) (ABIN1533464)

抗原

See all RCC1 抗体
RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

适用

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人, 小鼠, 大鼠

宿主

  • 86
  • 34
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兔

克隆类型

  • 76
  • 46
多克隆

标记

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This RCC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    AA 517-566

    原理

    XRCC1 Antibody

    特异性

    XRCC1 Polyclonal Antibody detects endogenous levels of XRCC1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

    别名

    RCC1

    背景

    Synonyms: XRCC1, DNA repair protein XRCC1, X-ray repair cross-complementing protein 1

    Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

    Gene Name: XRCC1

    Protein Name: DNA repair protein XRCC1

    分子量

    69 kDa

    基因ID

    7515

    OMIM

    194360

    UniProt

    P18887

    途径

    Chromatin Binding, Protein targeting to Nucleus
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