RCC1 抗体 (AA 517-566)
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北京 101111
Quick Overview for RCC1 抗体 (AA 517-566) (ABIN1533464)
抗原
See all RCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 517-566
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原理
- XRCC1 Antibody
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特异性
- XRCC1 Polyclonal Antibody detects endogenous levels of XRCC1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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别名
- RCC1
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背景
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Synonyms: XRCC1, DNA repair protein XRCC1, X-ray repair cross-complementing protein 1
Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
Gene Name: XRCC1
Protein Name: DNA repair protein XRCC1
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分子量
- 69 kDa
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基因ID
- 7515
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OMIM
- 194360
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UniProt
- P18887
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途径
- Chromatin Binding, Protein targeting to Nucleus
抗原
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