Vimentin 抗体 (AA 411-460)
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北京 101111
Quick Overview for Vimentin 抗体 (AA 411-460) (ABIN1533459)
抗原
See all Vimentin (VIM) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 411-460
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原理
- VIM Antibody
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特异性
- VIM Polyclonal Antibody detects endogenous levels of VIM protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Vimentin. AA range:411-460
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亚型
- IgG
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应用备注
- Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).
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- Vimentin (VIM)
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别名
- Vimentin
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背景
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Synonyms: VIM, Vimentin
Background: tumor protein p73(TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],
Gene Name: VIM
Protein Name: Vimentin
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分子量
- 53 kDa
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OMIM
- 193060
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UniProt
- P08670
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途径
- Caspase Cascade in Apoptosis
抗原
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