UBA7 抗体 (AA 963-1012)
Our Local Distributor
北京 101111
Quick Overview for UBA7 抗体 (AA 963-1012) (ABIN1533454)
抗原
See all UBA7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 963-1012
-
原理
- UBE1L Antibody
-
特异性
- UBE1L Polyclonal Antibody detects endogenous levels of UBE1L protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human UBE1L. AA range:963-1012
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
-
别名
- UBE1L
-
背景
-
Synonyms: UBA7, UBE1L, UBE2, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-activating enzyme 7, D8, Ubiquitin-activating enzyme E1 homolog
Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s.This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008],
Gene Name: UBA7
Protein Name: Ubiquitin-like modifier-activating enzyme 7
-
分子量
- 111 kDa
-
基因ID
- 7318
-
OMIM
- 191325
-
UniProt
- P41226
抗原
-