TOP2B 抗体 (AA 1-50)
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北京 101111
Quick Overview for TOP2B 抗体 (AA 1-50) (ABIN1533446)
抗原
See all TOP2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Topo IIβ Antibody
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特异性
- Topo IIβ Polyclonal Antibody detects endogenous levels of Topo IIβ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TOP2B. AA range:1-50
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亚型
- IgG
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anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (AA 446-655) antibody
TOP2B 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (C-Term) antibodyTOP2B 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (C-Term) antibodyTOP2B 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (N-Term) antibodyTOP2B 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (AA 1400-1626) antibodyTOP2B 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (AA 1475-1525) antibodyTOP2B 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (AA 1439-1488) antibodyTOP2B 适用: 人, 小鼠, 犬, 大鼠, 猴, Pig, 豚鼠, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (C-Term) antibodyTOP2B 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (AA 1548-1597) antibodyTOP2B 适用: 人, 小鼠, 犬, 大鼠, 猴, Pig, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) II beta 180kDa (TOP2B) (Middle Region) antibodyTOP2B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
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别名
- TOP2B
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背景
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Synonyms: TOP2B, DNA topoisomerase 2-beta, DNA topoisomerase II, beta isozyme
Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also pla
Gene Name: TOP2B
Protein Name: DNA topoisomerase 2-beta
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分子量
- 183 kDa
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基因ID
- 7155
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OMIM
- 126431
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UniProt
- Q02880
抗原
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