PIAS3 抗体 (AA 10-59)
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Quick Overview for PIAS3 抗体 (AA 10-59) (ABIN1533434)
抗原
See all PIAS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- PIAS 3 Antibody
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特异性
- PIAS 3 Polyclonal Antibody detects endogenous levels of PIAS 3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PIAS3. AA range:10-59
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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别名
- PIAS3
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背景
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Synonyms: PIAS3, E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3
Background: This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],
Gene Name: PIAS3
Protein Name: E3 SUMO-protein ligase PIAS3
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分子量
- 68 kDa
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基因ID
- 10401
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OMIM
- 605987
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UniProt
- Q9Y6X2
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途径
- JAK/STAT Signaling
抗原
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