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NUB1 抗体 (AA 566-615)

The 兔 多克隆 anti-NUB1 antibody (ABIN1533431) specifically detects NUB1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 猴 samples.
产品编号 ABIN1533431
发货至: 中国
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Quick Overview for NUB1 抗体 (AA 566-615) (ABIN1533431)

抗原

See all NUB1 抗体
NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

适用

  • 48
  • 26
  • 17
  • 16
  • 1
人, 小鼠, 猴

宿主

  • 43
  • 5
兔

克隆类型

  • 45
  • 3
多克隆

标记

  • 21
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NUB1 antibody is un-conjugated

应用范围

  • 41
  • 32
  • 30
  • 16
  • 14
  • 12
  • 7
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 566-615

    原理

    NUB1 Antibody

    特异性

    NUB1 Polyclonal Antibody detects endogenous levels of NUB1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human NYREN18. AA range:566-615

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

    别名

    NYREN18

    背景

    Synonyms: NUB1; NYREN18; NEDD8 ultimate buster 1; Negative regulator of ubiquitin-like proteins 1; Renal carcinoma antigen NY-REN-18

    Background: This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events.The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splici

    Gene Name: NUB1

    Protein Name: NEDD8 ultimate buster 1

    分子量

    70 kDa

    基因ID

    51667

    OMIM

    607981

    UniProt

    Q9Y5A7
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