HAT 抗体 (AA 331-380)
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北京 101111
Quick Overview for HAT 抗体 (AA 331-380) (ABIN1533428)
抗原
See all HAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-380
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原理
- HAT1 Antibody
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特异性
- HAT1 Polyclonal Antibody detects endogenous levels of HAT1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HAT. AA range:331-380
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HAT (Histone Acetyltransferase (HAT))
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别名
- HAT
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背景
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Synonyms: HAT1, KAT1, Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1
Background: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009],
Gene Name: HAT1
Protein Name: Histone acetyltransferase type B catalytic subunit
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分子量
- 49 kDa
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基因ID
- 8520
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OMIM
- 603053
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UniProt
- O14929
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途径
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
抗原
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