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TIMP1 抗体 (AA 61-110)

The 兔 多克隆 anti-TIMP1 antibody (ABIN1533419) specifically detects TIMP1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 大鼠, 小鼠 和 兔 samples.
产品编号 ABIN1533419
发货至: 中国
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Quick Overview for TIMP1 抗体 (AA 61-110) (ABIN1533419)

抗原

See all TIMP1 抗体
TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

适用

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  • 1
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人, 大鼠, 小鼠, 兔

宿主

  • 211
  • 87
  • 10
  • 1
  • 1
兔

克隆类型

  • 189
  • 120
多克隆

标记

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This TIMP1 antibody is un-conjugated

应用范围

  • 213
  • 112
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  • 45
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  • 26
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  • 22
  • 19
  • 11
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 30
    • 17
    • 15
    • 15
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    • 13
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    • 12
    • 10
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    • 2
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    AA 61-110

    原理

    TIMP-1 Antibody

    特异性

    TIMP-1 Polyclonal Antibody detects endogenous levels of TIMP-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human TIMP1. AA range:61-110

    亚型

    IgG
  • 应用备注

    IF 1:50-200 WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

    别名

    TIMP1

    背景

    Synonyms: TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1

    Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008],

    Gene Name: TIMP1

    Protein Name: Metalloproteinase inhibitor 1

    分子量

    23 kDa

    基因ID

    7076

    OMIM

    305370

    UniProt

    P01033
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