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CSTB 抗体 (AA 49-98)

The 兔 多克隆 anti-CSTB antibody (ABIN1533404) specifically detects CSTB in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN1533404
发货至: 中国
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Quick Overview for CSTB 抗体 (AA 49-98) (ABIN1533404)

抗原

See all CSTB 抗体
CSTB (Cystatin B (Stefin B) (CSTB))

适用

  • 141
  • 42
  • 25
  • 10
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 大鼠

宿主

  • 135
  • 29
  • 1
  • 1
兔

克隆类型

  • 111
  • 54
多克隆

标记

  • 62
  • 21
  • 11
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CSTB antibody is un-conjugated

应用范围

  • 124
  • 95
  • 44
  • 28
  • 23
  • 18
  • 13
  • 13
  • 12
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 43
    • 15
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 49-98

    原理

    Cystatin B Antibody

    特异性

    Cystatin B Polyclonal Antibody detects endogenous levels of Cystatin B protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Stefin B. AA range:49-98

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CSTB (Cystatin B (Stefin B) (CSTB))

    别名

    Stefin B

    背景

    Synonyms: CSTB, CST6, STFB, Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B

    Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens.This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG rep

    Gene Name: CSTB

    Protein Name: Cystatin-B

    分子量

    11 kDa

    基因ID

    1476

    OMIM

    601145

    UniProt

    P04080

    途径

    Response to Water Deprivation
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