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GUCYB 抗体 (AA 10-59)

The 兔 多克隆 anti-GUCYB antibody is suitable to detect GUCYB in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, WB, ELISA 和 IF.
产品编号 ABIN1533300
发货至: 中国
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Quick Overview for GUCYB 抗体 (AA 10-59) (ABIN1533300)

抗原

See all GUCYB 抗体
GUCYB (Guanylate Cyclase, beta (GUCYB))

适用

人, 小鼠, 大鼠

宿主

  • 10
兔

克隆类型

  • 10
多克隆

标记

  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GUCYB antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    AA 10-59

    原理

    GCS-β-1 Antibody

    特异性

    GCS-β-1 Polyclonal Antibody detects endogenous levels of GCS-β-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Guanylate Cyclase beta. AA range:10-59

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GUCYB (Guanylate Cyclase, beta (GUCYB))

    别名

    Guanylate Cyclase beta

    背景

    Synonyms: GUCY1B3, GUC1B3, GUCSB3, GUCY1B1, Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit

    Background: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

    Gene Name: GUCY1B3

    Protein Name: Guanylate cyclase soluble subunit beta-1

    分子量

    70 kDa

    基因ID

    2983

    OMIM

    139397

    UniProt

    Q02153
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