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GFRA1 抗体 (AA 51-100)

This 兔 多克隆 antibody specifically detects GFRA1 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533281
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GFRA1 抗体 (AA 51-100) (ABIN1533281)

抗原

See all GFRA1 抗体
GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

适用

人, 小鼠, 大鼠

宿主

  • 69
  • 5
  • 2
兔

克隆类型

  • 71
  • 5
多克隆

标记

  • 30
  • 7
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GFRA1 antibody is un-conjugated

应用范围

  • 45
  • 22
  • 21
  • 14
  • 14
  • 11
  • 11
  • 8
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-100

    原理

    GFRα-1 Antibody

    特异性

    GFRα-1 Polyclonal Antibody detects endogenous levels of GFRα-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GFR alpha-1. AA range:51-100

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

    别名

    GFR alpha-1

    背景

    Synonyms: GFRA1, GDNFRA, RETL1, TRNR1, GDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1

    Background: This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],

    Gene Name: GFRA1

    Protein Name: GDNF family receptor alpha-1

    分子量

    51 kDa

    基因ID

    2674

    OMIM

    601496

    UniProt

    P56159
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