Fibrillin 1 抗体 (AA 2811-2860)
Our Local Distributor
北京 101111
Quick Overview for Fibrillin 1 抗体 (AA 2811-2860) (ABIN1533275)
抗原
See all Fibrillin 1 (FBN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2811-2860
-
原理
- FBN1 Antibody
-
特异性
- FBN1 Polyclonal Antibody detects endogenous levels of FBN1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human Fibrillin-1. AA range:2811-2860
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Fibrillin 1 (FBN1)
-
别名
- Fibrillin-1
-
背景
-
Synonyms: FBN1, FBN, Fibrillin-1
Background: This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016],
Gene Name: FBN1
Protein Name: Fibrillin-1
-
分子量
- 312 kDa
-
基因ID
- 2200
-
OMIM
- 134797
-
UniProt
- P35555
-
途径
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
-