FHIT 抗体 (AA 81-130)
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北京 101111
Quick Overview for FHIT 抗体 (AA 81-130) (ABIN1533274)
抗原
See all FHIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-130
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原理
- Fhit Antibody
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特异性
- Fhit Polyclonal Antibody detects endogenous levels of Fhit protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FHIT. AA range:81-130
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FHIT (Fragile Histidine Triad (FHIT))
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别名
- FHIT
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背景
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Synonyms: FHIT; Bis(5'-adenosyl)-triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5'; 5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein
Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
Gene Name: FHIT
Protein Name: Bis(5'-adenosyl)-triphosphatase
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分子量
- 16 kDa
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基因ID
- 2272
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OMIM
- 601153
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UniProt
- P49789
抗原
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