Factor VIII 抗体 (AA 2161-2210)
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北京 101111
Quick Overview for Factor VIII 抗体 (AA 2161-2210) (ABIN1533268)
抗原
See all Factor VIII (F8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2161-2210
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原理
- Factor VIII Antibody
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特异性
- Factor VIII Polyclonal Antibody detects endogenous levels of Factor VIII protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Factor VIII. AA range:2161-2210
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亚型
- IgG
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anti-Coagulation Factor VIII (F8) (AA 2253-2346) antibody
F8 适用: 人 IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1887-2044) antibodyF8 适用: 人 IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1854-1988) antibodyF8 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1451-1550) antibodyF8 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 401-500) antibodyF8 适用: 大鼠 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 85-190) antibodyF8 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 213-312) antibodyF8 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Coagulation Factor VIII (F8) (AA 1-216) antibodyF8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (Middle Region) antibodyF8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1669-1824) antibodyF8 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Factor VIII (F8) (Coagulation Factor VIII (F8))
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别名
- Factor VIII
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背景
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Synonyms: F8, F8C, Coagulation factor VIII, Antihemophilic factor, AHF, Procoagulant component
Background: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008],
Gene Name: F8
Protein Name: Coagulation factor VIII
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分子量
- 267 kDa
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基因ID
- 2157
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OMIM
- 306700
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UniProt
- P00451
抗原
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