HSD17B10 抗体 (AA 111-160)
Our Local Distributor
北京 101111
Quick Overview for HSD17B10 抗体 (AA 111-160) (ABIN1533264)
抗原
See all HSD17B10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 111-160
-
原理
- ERAB Antibody
-
特异性
- ERAB Polyclonal Antibody detects endogenous levels of ERAB protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human ERAB. AA range:111-160
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
-
别名
- ERAB
-
背景
-
Synonyms: HSD17B10, ERAB, HADH2, MRPP2, SCHAD, XH98G2, 3-hydroxyacyl-CoA dehydrogenase type-2, 17-beta-hydroxysteroid dehydrogenase 10, 17-beta-HSD 10, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, Endoplasmic
Background: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014],
Gene Name: HSD17B10
Protein Name: 3-hydroxyacyl-CoA dehydrogenase type-2
-
分子量
- 26 kDa
-
基因ID
- 3028
-
OMIM
- 300220
-
UniProt
- Q99714
抗原
-