Cyclin F 抗体 (AA 737-786)
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北京 101111
Quick Overview for Cyclin F 抗体 (AA 737-786) (ABIN1533250)
抗原
See all Cyclin F (CCNF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 737-786
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原理
- Cyclin F Antibody
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特异性
- Cyclin F Polyclonal Antibody detects endogenous levels of Cyclin F protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Cyclin F. AA range:737-786
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cyclin F (CCNF)
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别名
- Cyclin F
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背景
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Synonyms: CCNF, FBX1, FBXO1, Cyclin-F, F-box only protein 1
Background: This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008],
Gene Name: CCNF
Protein Name: Cyclin-F
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分子量
- 87 kDa
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基因ID
- 899
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OMIM
- 600227
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UniProt
- P41002
抗原
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